DRG1 Maintains Intestinal Epithelial Cell Junctions and Barrier Function by Regulating RAC1 Activity in Necrotizing Enterocolitis.

Li LuWeijue XuJiangbin LiuLiping ChenShaohua HuQingfeng ShengMinghua ZhangZhibao Lv

Published in: Digestive diseases and sciences (2021)

Our findings illustrate the mechanism underlying the effect of DRG1 deficiency on epithelial cell permeability regulation and provide evidence supporting the application of RAC1 inhibitors for protection against NEC.

Keyphrases

cell migration
single molecule
endothelial cells
low birth weight
replacement therapy