Placental CD34 immunohistochemistry in fetal vascular malperfusion in stillbirth.
Jerzy StanekAlex DrachPublished in: The journal of obstetrics and gynaecology research (2022)
Most distal FVM lesions can be observed on hematoxylin-eosin placental slides only several days following the inciting event. CD34 immunostaining can reveal recent distal villous lesions of FVM featuring segmental villous endothelial fragmentation for de novo diagnosis or for upgrading FVM. Routine CD34 immunostaining has demonstrated FVM to be the major pattern of placental injury in stillborns.