Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification.

Ruth F DubinRajat DeoYue RenJianqiao WangAlexander R PicoJosyf C Mychaleckyi Julia KozlitinaVictoria ArthurHongzhe LeeAmil ShahHarold FeldmanNisha BansalLeila ZelnickPanduranga RaoNidhi SukulDominic S RajRupal MehtaSylvia E RosasZeenat BhatMatthew R WeirJiang HeJing ChenMayank KansalPaul L KimmelVasan S RamachandranSushrut S WaikarMark R SegalPeter Ganznull null

Published in: European heart journal (2024)

Large-scale proteomics reveal novel circulating protein biomarkers and potential mediators of HF in CKD. Proteomic risk models improve upon the PCP-HF risk score in this population.

Keyphrases

label free
heart failure
acute heart failure
mass spectrometry
chronic kidney disease
cardiovascular disease
genome wide
left ventricular
protein protein
atrial fibrillation
binding protein
amino acid
dna methylation
human health
cardiac resynchronization therapy
small molecule
risk assessment