Ca2+/calmodulin-dependent kinase IIδC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak.

Matthias DewenterTilmann SeitzJulia H SteinbrecherB Daan WestenbrinkHaiyun LingStephan E LehnartXander H T WehrensJohannes BacksJoan Heller BrownLars S MaierStefan Neef

Published in: ESC heart failure (2024)

leak-are critical for the maladaptive effects of chronically increased CaMKIIδC activity with respect to heart failure.

Keyphrases

protein kinase
heart failure
high glucose
diabetic rats
ejection fraction
drug induced
left ventricular
oxidative stress
atrial fibrillation
tyrosine kinase
acute heart failure