Ca2+/calmodulin-dependent kinase IIδC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak.

Matthias DewenterTilmann SeitzJulia H SteinbrecherB Daan WestenbrinkHaiyun LingStephan E LehnartXander H T WehrensJohannes BacksJoan Heller BrownLars S MaierStefan Neef

Published in: ESC heart failure (2024)

leak-are critical for the maladaptive effects of chronically increased CaMKIIδC activity with respect to heart failure.