Individuals with isolated congenital GH deficiency due to a GHRH receptor gene mutation appear to cope better with SARS-CoV-2 infection than controls.
Manuela A MeloLysandro P BorgesRoberto SalvatoriDaniela R V SouzaHertz T Santos-JúniorJosé M de R NetoViviane C CamposAryanne A SantosCarla R P OliveiraGrazielly B da InvençãoVanderlan O BatistaIgor L S MatosCynthia S Barros-OliveiraKezia A Dos SantosElenilde G SantosNicolas A A SouzaEnaldo V MeloPamela C BorgesSaulo E F S SantosBrenda M de OliveiraAlécia A Oliveira-SantosAmélia R de JesusManuel H Aguiar-OliveiraPublished in: Endocrine (2021)
The production of anti-SARS-CoV-2 antibodies was similar between IGHD subjects due to a GHRH receptor gene mutation and controls, but the evolution to symptomatic stages of the infection and the frequency of confirmed cases was lower in IGHD subjects than in GH sufficient individuals.