A Heterotypic Tridimensional Model to Study the Interaction of Macrophages and Glioblastoma In Vitro.
María José GattasIvana Gisele EstechoMaría Amparo Lago HuvelleAndrea Emilse ErrastiEugenio Antonio Carrera SilvaMarina SimianPublished in: International journal of molecular sciences (2021)
our results present a new physiologically relevant model to study GBM/macrophage interactions in a human setting and suggest that both soluble GBM factors, as well as cell-contact dependent signals, are strong inducers of anti-inflammatory macrophages within the tumor niche.