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Mitral valve disease in ankylosing spondylitis: an autoimmune disease manifestation? A case report.

Sulayman El MathariAllard van der WalHennie RatermanJolanda Kluin
Published in: European heart journal. Case reports (2022)
Histopathologic analysis showed chronic fibro inflammatory thickening of the MV leaflets and subvalvular apparatus. These pathological features could fit with the inflammatory nature of AS. Since this is a rare case, the recognition of fibro inflammatory thickening leading to commissural fusion and stenosis may contribute to better understanding of heart valve disease in AS to create a base for better cardiac management in this specific patient group.
Keyphrases
  • mitral valve
  • ankylosing spondylitis
  • rare case
  • oxidative stress
  • heart failure
  • left ventricular
  • rheumatoid arthritis
  • multiple sclerosis
  • disease activity
  • aortic stenosis
  • data analysis