Risk factors for granulomas in children following immunization with aluminium-adsorbed vaccines: A Danish population-based cohort study.
Stine Skovbo HoffmannEmilia Myrup ThiessonJeanne Duus JohansenAnders HviidPublished in: Contact dermatitis (2022)
Several risk factors for vaccination granulomas at the vaccine, child and maternal levels, were identified. Reducing the dose of aluminium or replacing aluminium hydroxide with aluminium phosphate could reduce the risk of granulomas. However, this must be balanced against the potential for reduced immunogenicity.