Review article: therapeutic bile acids and the risks for hepatotoxicity.
K AshbyE E Navarro AlmarioW TongJ BorlakR MehtaMinjun ChenPublished in: Alimentary pharmacology & therapeutics (2018)
Species differences should be considered in the development of bile acid related therapeutics. Although the mechanism of bile acid hepatotoxicity is still not fully understood, continued mechanistic studies will deepen our understanding.