Lipopolysaccharide-regulated secretion of soluble and vesicle-based proteins from a panel of colorectal cancer cell lines.

Cira R Garcia de DurangoMadalena N MonteiroIrene V BijnsdorpThang V PhamMeike De WitSander Rogier PiersmaJaco C KnolMarina Pérez-GordoRemond J A FijnemanFernando Vidal-VanaclochaConnie R Jiménez

Published in: Proteomics. Clinical applications (2021)

Bacterial endotoxin has minor impact on the global CRC cell line secretome, yet it may alter protein release in a cell line-specific manner. This modulation might play a role in orchestrating the development of a permissive environment for CRC liver metastasis, especially through EV-communication.

Keyphrases

inflammatory response
transcription factor
lps induced
protein protein
binding protein
amino acid
small molecule
immune response