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Red-shifted and pH-responsive imidazole-based azo dyes with potent antimicrobial activity.

Daniela DantasAna Isabel RibeiroFilipe CarvalhoEva Gil-MartinsRenata SilvaFernando RemiãoAndréa ZilleFátima CerqueiraEugénia PintoAlice Maria Dias
Published in: Chemical communications (Cambridge, England) (2023)
A novel route is described to obtain 2-aminoimidazole azo dyes with a unique substituent pattern in the heteroaryl unit that provides halochromic properties, exhibiting vibrant colours that change from magenta to deep blue. Potent antimicrobial properties against infectious yeasts were demonstrated. No cytotoxicity was detected for concentrations lower than 16 μg mL -1 .
Keyphrases
  • staphylococcus aureus
  • anti inflammatory
  • aqueous solution