The Effect of 3D-Printed Sequential Dual Drug-Releasing Patch on the Capsule Formation Around the Silicone Implant in a Rat Model.

Hyung Bae KimYeonggwon JoSoo Hyun WooSe Young HanSun Hyeok LeeYoung-Tae ChangJu Young ParkJinah JangHyun Ho Han

Published in: Aesthetic surgery journal (2024)

The 3D-printed dual drug-releasing patch effectively reduced inflammation and capsule formation in a rat model of silicone breast reconstruction. The beneficial effect of the dual drug-releasing patch was better than that of the antibiotic-only patch, indicating its therapeutic potential as a novel approach to prevent capsular contracture while reducing concerns of systemic side effects.

Keyphrases

breast reconstruction
oxidative stress
drug induced
adverse drug
emergency department
soft tissue