Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes.

Mikhail VysotskiyXue ZhongTyne W Miller-FlemingDan Zhounull nullnull nullnull nullNancy J CoxLauren A Weiss

Published in: Genome medicine (2021)

Our results demonstrate how integration of genetic and clinical data aids in understanding CNV gene function and implicates pleiotropy and multigenicity in CNV biology.

Keyphrases

genome wide
copy number
electronic health record
dna methylation
genome wide identification
gene expression
single cell
machine learning
antiretroviral therapy
artificial intelligence
deep learning