A novel mouse model of heatstroke accounting for ambient temperature and relative humidity.

Kazuyuki MiyamotoKeisuke SuzukiHirokazu OhtakiMotoyasu NakamuraHiroki YamagaMasaharu YagiKazuho HondaMunetaka HayashiKenji Dohi

Published in: Journal of intensive care (2021)

We developed a novel mouse heatstroke model that considered AT and RH. We found that ORS administration improved inadequate circulation and reduced tissue injury by increasing cotransporter gene expression in the intestines.

Keyphrases

gene expression
mouse model
air pollution
particulate matter
dna methylation