Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis.

Migliorini FilippoNicola MaffulliJörg EschweilerAlice BaronciniAndreas BellGiorgia Colarossi

Published in: Journal of orthopaedic surgery and research (2023)

Duloxetine could help in improving symptoms of fibromyalgia. The dose of duloxetine should be customised according to individual patients. Irrespective of the doses, duloxetine was more effective than placebo in the management of fibromyalgia. The dose of duloxetine must be customised according to individual patients. Level of evidence I Meta-analysis of double-blind RCTs.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
clinical trial
patient reported outcomes
depressive symptoms
sleep quality
phase ii
phase iii