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Leukotriene Receptor Antagonist, Montelukast Ameliorates L-NAME-Induced Pre-eclampsia in Rats through Suppressing the IL-6/Jak2/STAT3 Signaling Pathway.

Walaa Yehia AbdelzaherGomaa Mostafa-HedeabHaitham Ahmed BahaaAhmad MahranMichael Atef FawzySara Mohamed Naguib Abdel HafezNermeen N WelsonRemon Roshdy Rofaeil
Published in: Pharmaceuticals (Basel, Switzerland) (2022)
Mont exerted the biochemical and histopathological amelioration of L-NAME-caused pre-eclampsia through its anti-inflammatory, anti-oxidant function and suppression of the IL-6/Jak2/STAT3 signaling pathway.
Keyphrases
  • signaling pathway
  • anti inflammatory
  • pi k akt
  • epithelial mesenchymal transition
  • induced apoptosis
  • high glucose
  • diabetic rats
  • mouse model
  • endothelial cells