Electrogram fractionation during sinus rhythm occurs in normal voltage atrial tissue in patients with atrial fibrillation.
Antonio FronteraLuca Rosario LimiteStefano PaganiManuela CiredduKostantinos VlachosClaire MartinMasateru TakigawaTakeshi KitamuraFelix BourierGhassen ChnitiThomas PambrunFrederic SacherNicolas DervalMélèze HociniAlfio QuarteroniPaolo Della BellaMichel HaissaguerrePierre JaïsPublished in: Pacing and clinical electrophysiology : PACE (2022)
In patients with a history of AF, EGM fractionation can occur at amplitudes > 0.5 mV when in SR in areas often considered not to be diseased tissue. The main mechanism of EGM fractionation is slow conduction, followed by wavefront collision and pivot sites.