Mesenchymal Stem Cell Secreted-Extracellular Vesicles are Involved in Chondrocyte Production and Reduce Adipogenesis during Stem Cell Differentiation.

Yu-Chen TsaiTai-Shan ChengHsiu-Jung LiaoMing-Hsi ChuangHui-Ting ChenChun-Hung ChenKai-Ling ZhangChih-Hung ChangPo-Cheng LinChi-Ying F Huang

Published in: Tissue engineering and regenerative medicine (2022)

The results indicated that the production model could facilitate production of effective EVs and further demonstrated the role of MSC-derived EVs in cell differentiation. MSC-derived EVs could be successfully used in cell-free therapy to guide chondrogenic differentiation of ADSC for future clinical applications in cartilage regeneration.

Keyphrases

stem cells
cell free
mesenchymal stem cells
bone marrow
type diabetes
metabolic syndrome
umbilical cord
current status
circulating tumor
adipose tissue
smoking cessation