Ways of modulating GABA transporters to treat neurological disease.
Jonas Sigurd MortensenAmalie N L MikkelsenPetrine WellendorphPublished in: Expert opinion on therapeutic targets (2024)
The recent publication of various GAT1 structures is an important milestone for future development of compounds targeting the GATs. Such information can provide much needed insight into mechanistic aspects of all GAT subtypes and be utilized to design improved ligands for this highly interesting drug target class.