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The association between vertebral endplate defects, subchondral bone marrow changes, and lumbar intervertebral disc degeneration: a retrospective, 3-year longitudinal study.

Manuel MoserDominik Adl AminiLeonardo Albertini SanchezLisa OezelHenryk HafferMaximilian MuellnerJiaqi ZhuJohn A CarrinoJennifer ShueAndrew A SamaFrank P CammisaFederico P GirardiAlexander P Hughes
Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2023)
Our results suggest that TEPS does not unequivocally predict intervertebral DD in patients with LBP, since higher degrees of endplate defects might also develop secondarily to DD, and MC tend to occur late in the cascade of degeneration.
Keyphrases
  • bone marrow
  • mesenchymal stem cells
  • minimally invasive
  • bone mineral density
  • body composition
  • postmenopausal women