Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection.

Susanna S NgFernando Souza-Fonseca-GuimaraesFabian de Labastida RiveraFiona H AmanteRajiv KumarYulong GaoMeru SheelLynette BeattieMarcela Montes de OcaCamille GuillereyChelsea L EdwardsRebecca J FaleiroTeija FramePatrick T BunnEric VivierDale I GodfreyDaniel G PellicciJ Alejandro LopezKatherine T AndrewsNicholas D HuntingtonMark J SmythJames McCarthyChristian R Engwerda

Published in: Clinical & translational immunology (2018)

Our results show that ILC1s are lost early during mouse and human malaria, and this observation may help to explain the limited role for these cells in controlling blood stage infection.

Keyphrases

induced apoptosis
cell cycle arrest
endothelial cells
endoplasmic reticulum stress
signaling pathway
oxidative stress
plasmodium falciparum
cell death
induced pluripotent stem cells
quantum dots