Potential Mediators of Oxaliplatin-Induced Peripheral Neuropathy From Adjuvant Therapy in Stage III Colon Cancer: Findings From CALGB (Alliance)/SWOG 80702.

Seohyuk Lee Chao Ma Qian Shi Pankaj KumarFelix CouturePhilip KueblerSmitha KrishnamurthiDeQuincy LewisBenjamin TanRichard M Goldberg Alan P VenookCharles BlankeEileen M O'Reilly Anthony Frank Shields Jeffrey A Meyerhardt

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)

Lower physical activity, higher BMI, diabetes, and longer planned treatment duration, but not celecoxib use or vitamin B6 intake, may be associated with significantly increased OIPN severity.

Keyphrases

physical activity
body mass index
type diabetes
cardiovascular disease
high glucose
diabetic rats
glycemic control
drug induced
oxidative stress
depressive symptoms
metabolic syndrome
climate change
replacement therapy
sleep quality