The effect of unfractionated heparin, enoxaparin, and danaparoid on lupus anticoagulant testing: Can activated carbon eliminate false-positive results?

Pieter M M De Kesel Katrien M J Devreese

Published in: Research and practice in thrombosis and haemostasis (2019)

UFH, enoxaparin, and danaparoid clearly affected LA tests; however, false-positive LAC conclusions were obtained at supratherapeutic enoxaparin and danaparoid levels only. AC may prolong APTT screen clotting times, requiring 3-step testing to avoid potential misdiagnosis of LAC.

Keyphrases

venous thromboembolism
systemic lupus erythematosus
high throughput
disease activity
atrial fibrillation
rheumatoid arthritis
human health
risk assessment
single cell