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Paired APTTs of low and high lupus anticoagulant sensitivity permit distinction from other abnormalities and achieve good lupus anticoagulant detection rates in conjunction with dRVVT.

Osamu KumanoJean AmiralClaire DunoisMarie PeyrafitteGary W Moore
Published in: International journal of laboratory hematology (2018)
The percent correction of the APTT reagent pair showed higher values in LA-positive samples. The combination will be useful with respect to differentiating LA from other abnormal samples and is effective in LA detection when paired with dRVVT.
Keyphrases
  • systemic lupus erythematosus
  • atrial fibrillation
  • venous thromboembolism
  • loop mediated isothermal amplification
  • disease activity
  • real time pcr
  • label free
  • magnetic resonance imaging