Maternal hypertensive disorder of pregnancy and offspring early-onset cardiovascular disease in childhood, adolescence, and young adulthood: A national population-based cohort study.
Chen HuangJiong LiGuoyou QinZeyan LiewJing HuKrisztina D LászlóFangbiao TaoCarsten ObelJørn OlsenYongfu YuPublished in: PLoS medicine (2021)
Offspring born to mothers with HDP, especially mothers with CVD or diabetes history, were at increased risks of overall and certain type-specific early-onset CVDs in their first decades of life. Further research is warranted to better understand the mechanisms underlying the relationship between maternal HDP and early-onset CVD in offspring.
Keyphrases
- early onset
- cardiovascular disease
- high fat diet
- late onset
- pregnancy outcomes
- birth weight
- depressive symptoms
- type diabetes
- gestational age
- blood pressure
- early life
- preterm birth
- insulin resistance
- quality improvement
- pregnant women
- glycemic control
- metabolic syndrome
- cardiovascular risk factors
- human health
- physical activity
- climate change
- young adults