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Midbrain atrophy related to parkinsonism in a non-coding repeat expansion disorder: five cases of spinocerebellar ataxia type 31 with nigrostriatal dopaminergic dysfunction.

Ryohei NoriokaKeizo SugayaAki MurayamaTomoya KawazoeShinsuke TobisawaAkihiro KawataKazushi Takahashi
Published in: Cerebellum & ataxias (2021)
The clinical characteristics of the five patients with SCA31 with concomitant NSDD, together with the topographical pattern of atrophy, were inconsistent with PD, PSP, and multiple system atrophy, suggesting that SCA31 may manifest NSDD in association with the pathomechanisms underlying SCA31.
Keyphrases
  • oxidative stress
  • parkinson disease
  • drug induced