Efficacy and Safety of IL-12/23 and IL-23 Inhibitors for Crohn's Disease: Systematic Review and Meta-Analysis.
Sudheer Kumar VuyyuruVirginia SolitanoMalcolm HoganJohn K MacDonaldAlexa ZayadiClaire E ParkerBruce E SandsRemo PanaccioneNeeraj NarulaBrian G FeaganSiddharth SinghVipul JairathChristopher MaPublished in: Digestive diseases and sciences (2023)
Targeting IL-23 is effective and safe for inducing and maintaining clinical and endoscopic remission in patients with moderate-to-severe CD.