Relative contributions of the nervous system, spinal tissue and psychosocial health to non-specific low back pain: Multivariate meta-analysis.
Scott D TagliaferriSin-Ki NgBernadette M FitzgibbonPatrick J OwenClint T MillerSteven J BoweDaniel L BelavyPublished in: European journal of pain (London, England) (2021)
Spinal imaging (e.g. intervertebral disc degeneration), psychosocial (e.g. depression) and nervous system (e.g. quantitative sensory tests, structural and functional brain measures) biomarkers contribute to non-specific low back pain. However, psychosocial factors may be more compromised than nervous system and spinal imaging biomarkers. This relationship depends on if the pain is acute or chronic. These findings underscore that the 'non-specific' label in back pain should be reconsidered, and more specific multidimensional categories evaluated to guide patient management.
Keyphrases
- mental health
- high resolution
- spinal cord
- systematic review
- healthcare
- public health
- neuropathic pain
- liver failure
- depressive symptoms
- pain management
- case report
- meta analyses
- white matter
- respiratory failure
- drug induced
- spinal cord injury
- mass spectrometry
- resting state
- sleep quality
- health information
- brain injury
- climate change
- multiple sclerosis
- blood brain barrier
- aortic dissection
- intensive care unit
- fluorescence imaging