Splenic mass in a case of CALR-mutated essential thrombocythemia.

Shinsaku ImashukuShinichi KotaniJunsuke HinamiKeisuke Nishimura

Published in: Clinical case reports (2018)

We report here an intrasplenic large mass in an elderly case of essential thrombocythemia (ET)-myelofibrosis. Laparoscopic splenectomy revealed extramedullary hematopoiesis (EMH) and a type 1 CALR gene mutation (CALR-c.1092_1143del52) in the splenic mass. It remains to be determined if CALR-mutated ET has an increased tendency to develop mass-forming EMH.

Keyphrases

robot assisted
single cell
middle aged