PIK3CA mutations in breast cancer: A Tunisian series.
Mariem Ben RekayaSassi FarahEssya SaiedLinda Bel Haj KacemNada MansouriSinda ZarroukSaifeddine AzouzSoumaya RammehPublished in: PloS one (2023)
The frequency of somatic PIK3CA mutations in BCs of Tunisian women is slightly higher than that of BCs of Caucasian women and more observed in exon 9 than in exon 20. PIK3CA mutated status is associated with negative lymph node status. These data need to be confirmed in larger series.
Keyphrases
- lymph node
- polycystic ovary syndrome
- breast cancer risk
- pregnancy outcomes
- protein kinase
- cervical cancer screening
- neoadjuvant chemotherapy
- type diabetes
- big data
- squamous cell carcinoma
- adipose tissue
- insulin resistance
- pregnant women
- machine learning
- early stage
- young adults
- african american
- radiation therapy
- childhood cancer