Differences in 21-Gene and PAM50 Recurrence Scores in Younger and Black Women With Breast Cancer.

Sarah C Van Alsten Sanah N Vohra Joannie M Ivory Alina M Hamilton Xiaohua Gao Erin L KirkEboneé N ButlerHenry Shelton Earp Katherine E Reeder-Hayes Katherine A Hoadley Lisa Anne Carey Melissa A Troester

Published in: JCO precision oncology (2024)

differentially emphasize estrogen-related and proliferative biology. The emphasis of 21-gene RS on estrogen-related biology and lower endocrine therapy initiation among Black women may contribute to poorer prognostic ability in heterogeneously treated populations.

Keyphrases

copy number
estrogen receptor
polycystic ovary syndrome
genome wide identification
stem cells
gene expression
dna methylation
transcription factor
cell therapy
genome wide analysis