The role of NKX2-5 gene polymorphisms in congenital heart disease (CHD): a systematic review and meta-analysis.

Sana Ashiq Kanwal Ashiq Muhammad Farooq Sabar

Published in: The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology (2021)

Our findings suggested that 63A > G polymorphism in the NKX2-5 gene was not significantly associated with congenital heart defects. However, in the future, more studies with increased sample size are required that may provide us more definite conclusions.

Keyphrases

congenital heart disease
current status
copy number
genome wide
case control
gene expression
dna methylation
transcription factor