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Novel protein C6ORF120 promotes liver fibrosis by activating hepatic stellate cells through the PI3K/Akt/mTOR pathway.
Xin Wang
Hui Liu
Yuqi Wang
Peng Wang
Yunyun Yi
Yingying Lin
Xin Li
Published in:
Journal of gastroenterology and hepatology (2024)
C6ORF120 could activate hepatic stellate cells and promote hepatic fibrosis via the PI3K/Akt/mTOR signaling pathway.
Keyphrases
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induced apoptosis
signaling pathway
liver fibrosis
cell cycle arrest
pi k akt
endoplasmic reticulum stress
oxidative stress
epithelial mesenchymal transition
cell death
cell proliferation
amino acid
binding protein