Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure.

Tatiana V KarpinetsXiaogang WuTravis SolleyMolly B El AlamTravis T SimsKyoko Yoshida-CourtErica LynnMustapha Ahmed-KaddarGreyson BiegertJingyan YueXingzhi SongHuandong SunJoseph F PetrosinoMelissa P MezzariPablo OkhuysenPatricia J EifelAnuja JhingranLilie L LinKathleen M SchmelerLois RamondettaNadim AjamiRobert R JenqAndrew FutrealJianhua ZhangAnn H KloppLauren E Colbert

Published in: BMC cancer (2022)

In this study, enrichment of mucus degrading microbial communities in rectal metagenomes of CC patients was associated with larger, more advanced stage tumors.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
rectal cancer
prognostic factors
patient reported outcomes
young adults
patient reported