Prolonged Use of Proton Pump Inhibitors and Risk of Type 2 Diabetes: Results From a Large Population-Based Nested Case-Control Study.

Stefano Ciardullo Federico ReaLaura SavaréGabriella MorabitoGianluca Perseghin Giovanni Corrao

Published in: The Journal of clinical endocrinology and metabolism (2022)

Regular and prolonged use of PPIs is associated with a higher risk of diabetes. Physicians should therefore avoid unnecessary prescription of this class of drugs, particularly for long-term use.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
primary care
insulin resistance
adipose tissue
drug induced