Mood disorders increase mortality mainly through dementia: A community-based prospective cohort study.
Hoyoung AnHee Won YangDae Jong OhEunji LimJin ShinDong Gyu MoonSeung Wan SuhSeonjeong ByunTae Hui KimKyung Phil KwakBong Jo KimShin Gyeom KimJeong Lan KimSeok Woo MoonJoon Hyuk ParkSeung-Ho RyuDong Woo LeeSeok Bum LeeJung Jae LeeJin Hyeong JhooJong Bin BaeJi Won HanYou Joung KimPublished in: The Australian and New Zealand journal of psychiatry (2021)
Both depressive and bipolar disorders increased the risks of mortality and dementia, and the effects of mood disorders on mortality were mainly mediated through dementia. As dementia occurs later in life than mood disorders, measures to prevent it may effectively reduce mortality in individuals with a history of mood disorders, as well as being more feasible than attempting to control other causes of death.