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Pyridazine Derivatives as NLRP3 Inhibitors for Treating Asthma, COPD, Parkinson's Disease, and Alzheimer's Disease.

Rachel Mata
Published in: ACS medicinal chemistry letters (2023)
Provided herein are novel pyridazine derivatives as NLRP3 inhibitors, pharmaceutical compositions, use of such compounds in treating asthma, COPD, Parkinson's disease, and Alzheimer's disease, and processes for preparing such compounds.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • cognitive decline
  • cystic fibrosis