Therapeutic Effects of Modified Si-Miao-Yong-An Decoction in the Treatment of Rat Myocardial Ischemia/Reperfusion Injury.

Chen Wang Yahong Wang Dandan Song Jing Su Fangyuan Zhang

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

The results indicated that MSMYA played an important role in protecting the myocardium from I/R injury. The likely mechanism is the inhibition of oxidative stress, improvement of cardiac injury, and the reduction of NLRP3-related inflammatory cytokines release. This provides a basis for further research on the mechanism and clinical application of MSMYA to improve myocardial I/R injury.

Keyphrases

oxidative stress
ischemia reperfusion injury
left ventricular
dna damage
signaling pathway
nlrp inflammasome
atrial fibrillation