Optimizing the dosing of vancomycin in patients receiving intermittent haemodialysis with low-flux filters, and the potential impact of dosing software.

Maurizio StefaniKirsty MusgraveJacob SevastosMark PennyRichard Osborne Day Darren M Roberts

Published in: Nephrology (Carlton, Vic.) (2023)

Vancomycin dosing was suboptimal and the pharmacokinetic software was not sufficiently predictive. These may improve with a loading dose. The substantial removal of vancomycin by low-flux filters is not accounted for by the models tested.

Keyphrases

methicillin resistant staphylococcus aureus
data analysis
high intensity
peritoneal dialysis
chronic kidney disease