Genetic architecture of mammographic density as a risk factor for breast cancer: a systematic review.

Asma Khorshid ShamshiriMaryam AlidoustMahboubeh Hemmati NokandeiAlireza PasdarFahimeh Afzaljavan

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2023)

Genes involved in developmental processes and the evolution of secondary sexual traits play an important role in determining mammographic density. Due to the effect of breast tissue density on the risk of breast cancer, these genes may also be associated with breast cancer risk.

Keyphrases

breast cancer risk
genome wide
dna methylation
copy number
gene expression
young adults