Influence of drug safety advisories on drug utilisation: an international interrupted time series and meta-analysis.
Richard L MorrowBarbara J MintzesPatrick C SouvereinMarie L De BruinElizabeth Ellen RougheadJoel LexchinAnna Kemp-CaseyLorri PuilIngrid SketrisDee ManginChristine Erikstrup HallgreenSallie-Anne PearsonRuth LopertLisa BeroRichard Ofori-AsensoDanijela GnjidicAmeet SarpatwariLucy T PerryColin R DormuthPublished in: BMJ quality & safety (2022)
Among safety advisories issued on a wide range of drugs during 2009-2015 in 4 countries (Canada, Denmark, the UK and the USA), the association of advisories with changes in drug utilisation was variable, and the average association was modest.