Sunscreen applied at ≥ 2 mg cm-2 during a sunny holiday prevents erythema, a biomarker of ultraviolet radiation-induced DNA damage and suppression of acquired immunity.

J NarbuttPeter Alshede PhilipsenG I HarrisonK A MorganKarl P LawrenceK A BaczynskaK GrysM Rogowski-TylmanI Olejniczak-StaruchAngela TewariM BellC O'ConnorH C WulfA LesiakAntony R Young

Published in: The British journal of dermatology (2018)

Optimal sunscreen use prevents erythema during a sunny holiday. Erythema predicts suppression of CHS (implying a shared action spectrum). Given that erythema and CPDs share action spectra, the data strongly suggest that optimal sunscreen use will also reduce CPD formation and UVR-induced immunosuppression.

Keyphrases

radiation induced
dna damage
radiation therapy
oxidative stress
mouse model
diabetic rats
high glucose
electronic health record
machine learning
dna repair
big data
endothelial cells
density functional theory
data analysis
molecular dynamics