Safety and biologic activity of a canine anti-CD20 monoclonal antibody in dogs with diffuse large B-cell lymphoma.

Gretchen P McLindenAnne C AveryHeather L GardnerKelley HughesAngie M RoddayKexuan LiangCheryl A London

Published in: Journal of veterinary internal medicine (2024)

The canine 1E4-cIgGB anti-CD20 monoclonal antibody is apparently safe when administered with doxorubicin and effectively depletes B-cells in dogs with DLBCL.

Keyphrases

monoclonal antibody
diffuse large b cell lymphoma
epstein barr virus
rheumatoid arthritis
nk cells
drug delivery
cancer therapy