pH-Responsive Nanocomposite Based Hydrogels for the Controlled Delivery of Ticagrelor; In Vitro and In Vivo Approaches.
Nariman ShahidAlia ErumMuhammad ZamanUme Ruqia TulainQurat-Ul-Ain ShoaibAbdul MajeedMuhammad Fawad RasoolImran ImranSultan M AlshehriBehnam NooraniFaleh AlqahtaniPublished in: International journal of nanomedicine (2021)
The results suggest that NCHs demonstrated a pH-responsive, controlled behavior along with enhanced bioavailability. Thus NCHs can be effectively utilized as efficient delivery systems for oral delivery of TG to reduce the risk of myocardial infarction.
Keyphrases
- acute coronary syndrome
- heart failure
- percutaneous coronary intervention
- drug delivery
- left ventricular
- antiplatelet therapy
- quantum dots
- reduced graphene oxide
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- hyaluronic acid
- drug release
- wound healing
- gold nanoparticles
- tissue engineering
- tandem mass spectrometry