Correlation between B cell epitope profile and clinical features of anti-MDA5 antibody-positive dermatomyositis.

Koichi YamaguchiPaul PolandTissa Bijoy GeorgeDidem SayginSiamak Moghadam-KiaRohit AggarwalChester V OddisLei ZhuDana P Ascherman

Published in: Rheumatology (Oxford, England) (2023)

Various clinical features of MDA5+ dermatomyositis correlated with levels of antibodies targeting selected subfragments of this autoantigen, providing a link between fragment-specific immune responses and disease course.

Keyphrases

interstitial lung disease
breast cancer cells
immune response
systemic sclerosis
disease activity
rheumatoid arthritis
cell cycle arrest
idiopathic pulmonary fibrosis
cancer therapy
systemic lupus erythematosus
toll like receptor
dendritic cells
inflammatory response