Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice.

Chengcheng GaiXiaohui XingYan SongYijing ZhaoZige JiangYahong ChengYilei XiaoZhen Wang

Published in: Drug design, development and therapy (2023)

The study indicates that miR-9-5p-mediated HI injury is regulated by DDIT4-mediated autophagy pathway and up-regulation of miR-9-5p level may provide a potential therapeutic effect on HI brain damage.

Keyphrases

oxidative stress
cell death
white matter
resting state
endothelial cells
type diabetes
multiple sclerosis
insulin resistance
brain injury
human health