Hypoxic Preconditioning Enhances Bone Marrow-Derived Mesenchymal Stem Cell Survival in a Low Oxygen and Nutrient-Limited 3D Microenvironment.

Sun H PeckJustin R BendigoJohn W TobiasGeorge R DodgeNeil R MalhotraRobert L MauckLachlan J Smith

Published in: Cartilage (2019)

These results strongly support the use of hypoxic preconditioning to improve postimplantation MSC survival in avascular tissues such as disc and cartilage.

Keyphrases

mesenchymal stem cells
ischemia reperfusion injury
stem cells
free survival
cerebral ischemia
gene expression
bone marrow
umbilical cord
extracellular matrix
subarachnoid hemorrhage