A unique group of scabies mite pseudoproteases promotes cutaneous blood coagulation and delays plasmin-induced fibrinolysis.
Deepani Darshika FernandoSimone L ReynoldsGunter F HartelBernard CribierNicolas OrtonneMalcolm K JonesKatja FischerPublished in: PLoS neglected tropical diseases (2021)
The SMIPP-Cs are the first scabies mite proteins found in sub-epidermal skin layers and their pro-coagulant properties promote superficial microthrombi formation in scabetic skin. Further research is needed to evaluate their potential as diagnostic or therapeutic target.