Alternative metrics for characterizing longer-term clinical outcomes in difficult-to-treat depression: II. Sensitivity to treatment effects.
Scott T AaronsonHarold A SackeimMei JiangSarah BadejoTeresa GrecoMark T BunkerCharles R ConwayKoen DemyttenaereAllan H YoungR Hamish McAllister-WilliamsA John RushPublished in: The Australian and New Zealand journal of psychiatry (2023)
In difficult-to-treat depression, integrative symptom severity-based and time-based measures are sensitive and informative outcomes for assessing between-group treatment effects, while metrics based on remission status are not.