Postoperative atrial fibrillation: from mechanisms to treatment.
Mario F L GaudinoAntonino Di FrancoLisa Qia RongJonathan PicciniMichael MackPublished in: European heart journal (2023)
Postoperative atrial fibrillation (POAF) is the most common type of secondary atrial fibrillation (AF) and despite progress in prevention and treatment, remains an important clinical problem for patients undergoing a variety of surgical procedures, and in particular cardiac surgery. POAF significantly increases the duration of postoperative hospital stay, hospital costs, and the risk of recurrent AF in the years after surgery; moreover, POAF has been associated with a variety of adverse cardiovascular events (including stroke, heart failure, and mortality), although it is still unclear if this is due to causal relation or simple association. New data have recently emerged on the pathophysiology of POAF, and new preventive and therapeutic strategies have been proposed and tested in randomized trials. This review summarizes the current evidence on the pathogenesis, incidence, prevention, and treatment of POAF and highlights future directions for clinical research.
Keyphrases
- atrial fibrillation
- patients undergoing
- cardiovascular events
- heart failure
- cardiac surgery
- oral anticoagulants
- left atrial
- catheter ablation
- direct oral anticoagulants
- healthcare
- left atrial appendage
- risk factors
- acute kidney injury
- machine learning
- emergency department
- acute coronary syndrome
- type diabetes
- combination therapy
- subarachnoid hemorrhage
- current status
- cardiac resynchronization therapy
- acute care